Publications from the Gothenburg team

Publications of the Gothenburg team

Our original publications in this area are given below, from our first publication which was published in 2002 to our most recent publication. A number of additional research articles in this area are in the process of publication.


Vascular pedicle lengths after hysterectomy: toward future human uterus transplantation.
Johannesson L, Diaz-Garcia C, Leonhardt H, Dahm-Kähler P, Marcickiewicz J, Olausson M, Brännström M.
Obstet Gynecol. 2012 Jun;119(6):1219-25.

Effects of immunosuppression by cyclosporine A on allogenic uterine transplant in the rat.
Groth K, Akhi SN, Mölne J, Wranning CA, Brännström M.
Eur J Obstet Gynecol Reprod Biol. 2012 Jul;163(1):97-103. Epub 2012 Apr 13.
PMID: 22502817 .

Uterus transplantation in a non-human primate: long-term follow-up after autologous transplantation.
Johannesson L, Enskog A, Dahm-Kähler P, Hanafy A, Chai DC, Mwenda JM, Díaz-García C, Olausson M, Brännström M.
Hum Reprod. 2012 Jun;27(6):1640-8. Epub 2012 Mar 27. PMID: 22454459

Preclinical nonhuman primate report on allogeneic uterus transplantation
L Johannesson, Enskog, Mölne, Dahm-Kähler, Tekin, Diaz-Garcia, Hanafy, Ruiz, Tzakis, Olaussong and Brännström Hum Reprod in press

Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus
Akhi, Diaz-Garcia, El-Akouri, Wranning, Mölne, Brännström, Fertil Steril in press


Pregnancy after syngeneic uterus transplantation and spontaneous mating in the rat.
Wranning CA, Akhi SN, Diaz-Garcia C, Brännström M.
Hum Reprod. 2011 Mar;26(3):553-8. Epub 2010 Dec 15.
PMID: 21159686

First report on fertility after allogeneic uterus transplantation.
Díaz-García C, Akhi SN, Wallin A, Pellicer A, Brännström M.
Acta Obstet Gynecol Scand. 2010 Nov;89(11):1491-4. Epub 2010 Sep 30.
PMID: 20879912


Uterus transplantation in the baboon: methodology and long-term function after auto-transplantation.
Enskog A, Johannesson L, Chai DC, Dahm-Kähler P, Marcickiewicz J, Nyachieo A, Mwenda JM, Brännström M.
Hum Reprod. 2010 Aug;25(8):1980-7. Epub 2010 Jun 2.
PMID: 20519250

Fertility after autologous ovine uterine-tubal-ovarian transplantation by vascular anastomosis to the external iliac vessels.
Wranning CA, Marcickiewicz J, Enskog A, Dahm-Kähler P, Hanafy A, Brännström M.
Hum Reprod. 2010 Aug;25(8):1973-9. Epub 2010 Jun 2.
PMID: 20519245

Cyclosporine A exposure during pregnancy in mice: effects on reproductive performance in mothers and offspring.
Groth K, Brännström M, Mölne J, Wranning CA.
Hum Reprod. 2010 Mar;25(3):697-704. Epub 2010 Jan 18.
PMID: 20085916


Rejection of allogenic uterus transplant in the mouse: time-dependent and site-specific infiltration of leukocyte subtypes.
Groth K, Akouri R, Wranning CA, Mölne J, Brännström M.
Hum Reprod. 2009 Nov;24(11):2746-54. Epub 2009 Jul 17.
PMID: 19617209

Heterotopic uterus transplantation in a swine model.
Avison DL, DeFaria W, Tryphonopoulos P, Tekin A, Attia GR, Takahashi H, Jin Y, Palaios E, Pararas N, Carreno MR, Santiago S, Bazer F, Ruiz P, Tzakis A.
Transplantation. 2009 Aug 27;88(4):465-9.
PMID: 19696628


Uterus transplantation in the rat: model development, surgical learning and morphological evaluation of healing.
Wranning CA, Akhi SN, Kurlberg G, Brännström M.
Acta Obstet Gynecol Scand. 2008;87(11):1239-47.
PMID: 18951268

Transplantation of the uterus in sheep: methodology and early reperfusion events.
Dahm-Kähler P, Wranning C, Lundmark C, Enskog A, Mölne J, Marcickiewicz J, El-Akouri RR, McCracken J, Brännström M.
J Obstet Gynaecol Res. 2008 Oct;34(5):784-93.
PMID: 18834335

Transplantation of the uterus in the sheep: oxidative stress and reperfusion injury after short-time cold storage.
Wranning CA, Dahm-Kähler P, Mölne J, Nilsson UA, Enskog A, Brännström M.
Fertil Steril. 2008 Sep;90(3):817-26. Epub 2007 Sep 27.
PMID: 17904131


Rejection of the transplanted uterus is suppressed by cyclosporine A in a semi-allogeneic mouse model.
Wranning CA, El-Akouri RR, Groth K, Mölne J, Parra AK, Brännström M.
Hum Reprod. 2007 Feb;22(2):372-9. Epub 2006 Oct 24.
PMID: 17062584


Auto-transplantation of the uterus in the domestic pig (Sus scrofa): Surgical technique and early reperfusion events.
Wranning CA, El-Akouri RR, Lundmark C, Dahm-Kähler P, Mölne J, Enskog A, Brännström M.
J Obstet Gynaecol Res. 2006 Aug;32(4):358-67.
PMID: 16882260

Rejection patterns in allogeneic uterus transplantation in the mouse.
El-Akouri RR, Mölne J, Groth K, Kurlberg G, Brännström M.
Hum Reprod. 2006 Feb;21(2):436-42. Epub 2005 Oct 27.
PMID: 16253976


Short-term ischaemic storage of human uterine myometrium–basic studies towards uterine transplantation.
Wranning CA, Mölne J, El-Akouri RR, Kurlberg G, Brännström M.
Hum Reprod. 2005 Oct;20(10):2736-44. Epub 2005 Jun 24.
PMID: 15980004


Pregnancy in transplanted mouse uterus after long-term cold ischaemic preservation.
Racho El-Akouri R, Wranning CA, Mölne J, Kurlberg G, Brännström M.
Hum Reprod. 2003 Oct;18(10):2024-30.
PMID: 14507816

Successful uterine transplantation in the mouse: pregnancy and post-natal development of offspring.
Racho El-Akouri R, Kurlberg G, Brännström M.
Hum Reprod. 2003 Oct;18(10):2018-23.
PMID: 14507815


Heterotopic uterine transplantation by vascular anastomosis in the mouse.
Racho El-Akouri R, Kurlberg G, Dindelegan G, Mölne J, Wallin A, Brännström M.
J Endocrinol. 2002 Aug;174(2):157-66.
PMID: 12176655

Summary articles

The group’s summary articles in uterus transplant area are given below:

Uterus transplantation: animal research and human possibilities.
Brännström M, Diaz-Garcia C, Hanafy A, Olausson M, Tzakis A.
Fertil Steril. 2012 Jun;97(6):1269-76. Epub 2012 Apr 28. Review.
PMID: 22542990

Uterine transplantation research: laboratory protocols for clinical application.
Díaz-García C, Johannesson L, Enskog A, Tzakis A, Olausson M, Brännström M.
Mol Hum Reprod. 2012 Feb;18(2):68-78. Epub 2011 Sep 7.
PMID: 21900333

Uterine transplantation: one human case followed by a decade of experimental research in animal models.
Hanafy A, Diaz-Garcia C, Olausson M, Brännström M.
Aust N Z J Obstet Gynaecol. 2011 Jun;51(3):199-203. doi: 10.1111/j.1479-828X.2010.01283.x. Epub 2011 Feb 7. Review.
PMID: 21631436

Transplantation of female genital organs.
Brännström M, Díaz-García C.
J Obstet Gynaecol Res. 2011 Apr;37(4):271-91. doi: 10.1111/j.1447-0756.2010.01416.x. Epub 2011 Feb 23. Review.
PMID: 21349131

Experimental uterus transplantation.
Brännström M, Wranning CA, Altchek A.
Hum Reprod Update. 2010 May-Jun;16(3):329-45. Epub 2009 Nov 7. Review.
PMID: 19897849

Uterus transplantation: how far away from human trials?
Brännström M, Wranning CA.
Acta Obstet Gynecol Scand. 2008;87(11):1097-100.
PMID: 18951223

Uterine transplantation: a future possibility to treat women with uterus factor infertility?
Brännström M.
Minerva Med. 2007 Jun;98(3):211-6. Review.
PMID: 17592442

Uterus transplantation: where do we stand today and where should we go?
Brännström M, Wranning CA.
Expert Opin Biol Ther. 2007 Apr;7(4):427-9. Review.
PMID: 17373894

Uterine transplantation.
Brännström M, Racho El-Akouri R, Wranning CA.
Eur J Obstet Gynecol Reprod Biol. 2003 Aug 15;109(2):121-3. Review.
PMID: 12860325

Transplantation of the uterus.
Brännström M, Wranning CA, Racho El-Akouri R.
Mol Cell Endocrinol. 2003 Apr 28;202(1-2):177-84. Review.
PMID: 12770748